Alma Therapeutic's Capsule
Alma's capsule provides a unique platform for oral delivery of therapeutic proteins and peptides which possess poor oral bioavailability, necessitating administration via injections.
The company’s technology utilizes a microneedles - array approach for advanced oral delivery.
This is a novel needle‐free alternative to injectable drugs that can enhance quality of life for millions of people requiring chronic administration of injectable drugs.
Alma Therapeutics advantages
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Enhances patient compliance: pain free and non invasive
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Addresses unmet need: quick and easy, highly specified treatments
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Effectively delivers biotherapeutic drugs
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Bypasses biologic barriers
The Gastro-Resistant coated capsule moves along the GI tract and dissolves in the alkaline pH of the upper part of the small intestine
Biodegradable microneedles loaded with biologic medicines penetrate through the intestinal epithelium layer, delivering their cargo (e.g., antibodies, peptides, enzymes) and enabling systemic drug absorption
The flexible patch is released from the capsule, expands, and orients the biodegradable microneedles towards the intestinal mucosa
The flexible patch detaches from the intestinal wall and is naturally excreted with the intestinal liquids